protein biosynthesis

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protein biosynthesis

gord-6
Hello All

    I would like to know to which end of the elongating protein chain,
during biosysnthesis, is the next amino acid attached. Amino or carboxyl.

Thank you.

Gord


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RE: Protein biosynthesis

David Bienvenue

Protein biosynthesis starts at the N-terminus.  



David Bienvenue, Ph.D.
Senior Principal Scientist
VLST Corporation
Seattle, WA 98109


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Message: 1
Date: Sun, 23 Aug 2009 18:27:49 -0400
From: "gord" <[hidden email]>
Subject: [Protein-analysis] protein biosynthesis
To: [hidden email]
Message-ID: <Gnjkm.114076$[hidden email]>

Hello All

    I would like to know to which end of the elongating protein chain,
during biosysnthesis, is the next amino acid attached. Amino or carboxyl.

Thank you.

Gord




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Re: Protein biosynthesis

gord-6
In reply to this post by gord-6
Thank you very much for your reply

Gord

"David Bienvenue" <[hidden email]> wrote in message
news:[hidden email]...

>
> Protein biosynthesis starts at the N-terminus.
>
>
>
> David Bienvenue, Ph.D.
> Senior Principal Scientist
> VLST Corporation
> Seattle, WA 98109
>
>
> -----Original Message-----
> From: [hidden email]
> [mailto:[hidden email]] On Behalf Of
> [hidden email]
> Sent: Monday, August 24, 2009 10:04 AM
> To: [hidden email]
> Subject: Proteins Digest, Vol 51, Issue 3
>
> Send Proteins mailing list submissions to
> [hidden email]
>
> To subscribe or unsubscribe via the World Wide Web, visit
> http://www.bio.net/biomail/listinfo/proteins
> or, via email, send a message with subject or body 'help' to
> [hidden email]
>
> You can reach the person managing the list at
> [hidden email]
>
> When replying, please edit your Subject line so it is more specific
> than "Re: Contents of Proteins digest..."
>
>
> Today's Topics:
>
>   1. protein biosynthesis (gord)
>
>
> ----------------------------------------------------------------------
>
> Message: 1
> Date: Sun, 23 Aug 2009 18:27:49 -0400
> From: "gord" <[hidden email]>
> Subject: [Protein-analysis] protein biosynthesis
> To: [hidden email]
> Message-ID: <Gnjkm.114076$[hidden email]>
>
> Hello All
>
>    I would like to know to which end of the elongating protein chain,
> during biosysnthesis, is the next amino acid attached. Amino or carboxyl.
>
> Thank you.
>
> Gord
>
>
>
>
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>
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Re: Protein biosynthesis

kaj.stenberg
In reply to this post by gord-6
David Bienvenue <[hidden email]> wrote:

> Protein biosynthesis starts at the N-terminus.  

However, this means that each new amino acid is attached to the
C-terminus of the growing peptide.

--
Kaj
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Re: Protein biosynthesis

Dr Engelbert Buxbaum
Am 25.08.2009, 03:48 Uhr, schrieb <[hidden email]>:

> David Bienvenue <[hidden email]> wrote:
>
>> Protein biosynthesis starts at the N-terminus.
>
> However, this means that each new amino acid is attached to the
> C-terminus of the growing peptide.

And note that above is true only for biological protein synthesis,  
chemists do it the other way round (Merrifield peptide synthesis). In case  
of daubt, it is worthwhile to write peptides like NH2-XXXXX-COOH (I have  
been burned!)
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