Proteomics/Biomarkers Patents & Research News (1/6/09)

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Proteomics/Biomarkers Patents & Research News (1/6/09)


US Patents issued (1/5/09)

1. A mass spectrometry method and a new mass spectroscope for the
analysis of proteins larger than 100 KDa
2. Ultra high mass range mass spectrometer systems for the analysis of
proteins larger than 100 KDa
3. Ion trap mass spectrometry analysis of proteins with molecular
weights  5 to 100 kilodaltons, without enzymatic digestion to small
4. Protein arrays: protein attachment to solid supports using
incorporated unnatural amino acids
5. Vimentin as a biomarker for prostate cancer
6. A novel 161P5C5 protein/gene as a biomarker for cancer
7. Immunosubtraction method for the removal of high abundant proteins
8. Microfluidic apparatus for performing 2-D separation of proteins
9. A gel electroelution device for proteins

Recent research articles

1.Ubiquitin as a biomarker for Creutzfeldt-Jakob disease
2.GTPases profiling by capture compound mass spectrometry (CCMS)
3. Apolipoprotein A-I, Plasma retinol-binding protein, Gelsolin, and
Vitamin D-binding protein as biomarkers for Klinefelter syndrome
4. High throughput MALDI imaging
6. MRM assay using laser-microdissected paraffin-embedded tissues
7. Glycoproteins (tumor rejection antigen (gp96) 1, triose phosphate
isomerase, palmitoyl-protein thioesterase 1 precursor and ER-
associated DNAJ) as biomarkers for paclitaxel resistance in ovarian
8. Ex-vivo serum biomarkers in multiple sclerosis are linked to
modifications generated during - 20 °C storage
9. A centrifugal ultrafiltration method for the isolation of low-
molecular weight proteins
10. Protein carbonylation detected by isotope-labeled DNPH

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